Chapter six details the opening of the six seals. The events that occur from the opening of the six seals are as follows:
| Seal | Event | Meaning |
| Seal 1 | White horse with a mounted archer. | Foreign invasion |
| Seal 2 | Red horse with a rider who takes peace from the earth | Internal uprising |
| Seal 3 | Blake horse with a rider holding scales announcing inflation | Famine |
| Seal 4 | Pale green horse whose rider was named “death” | Death |
| Seal 5 | Martyrs cry out from under the altar requesting vindication | Anticipation of judgment |
| Seal 6 | Earthquake causing the luminaries to fall/darken | Complete catastrophe |
